Determining NVR Extractable from Swabs

Test Method 10Test Method 10

Procedure for Determining the Nonvolatile Residue (NVR) Extractable from Swabs in a Given Solvent

Swabs are not only present in the cleanroom, but are normally used directly on the products being manufactured or in critical sampling procedures. One form of swab contamination is the soluble matter extractable in a given cleaning solvent (nonvolatile residue or NVR). NVR contamination can remain on a surface after cleaning with a wetted swab.

"The choice of any material in a cleanroom is critical in terms of the contamination it may contribute to the environment. Swabs are not only present in the cleanroom, but are normally used directly on the products being manufactured or in critical sampling procedures. One form of swab contamination is the soluble matter extractable in a given cleaning solvent (nonvolatile residue or NVR).

NVR contamination can remain on a surface after cleaning with a wetted swab. It is therefore imperative that there be some method of qualification of such materials. Procedures have been drafted in the past to address this issue with textiles and other materials. This procedure addresses the issue as related to swabs and allows for the extraction and determination of the total mass of soluble matter of a swab in a given solvent..."